cannabis and depression study

Endocannabinoids and Depression

Scientists are studying chronic stress and depression, and at the University of Buffalo’s Research Institute on Addictions (RIA), they are focusing on the endocannabinoids, which are brain chemicals similar to substances found in Cannabis. Endocannabinoids are natural chemical compounds in the brain that affect motor control, cognition, emotions, and behavior. They are similar to the chemicals found in marijuana (Cannabis sativa) and it’s active ingredient, THC. Thus far limited to animal studies, it was found that chronic stress reduced the production of endocannabinoids, leading to depression-like behavior. The findings raise the possibility that components of Cannabis may be useful in reducing depression that results from chronic stress.